Is It Safe to Buy Esketamine Nasal Spray Online?

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Depression is a common health condition. It is estimated that 3.8% of the population worldwide is affected by depression. And while many of these patients may find relief using oral antidepressant medication or psychotherapy, others do not.

Esketamine, also called Spravato®, is a type of ketamine that is increasingly being used as an alternative option for treatment-resistant depression, major depressive disorder, and those who suffer from acute suicidal thoughts.

But before considering whether esketamine may be right for you, it’s crucial that you understand essential safety information and risks that may come with taking Spravato®. And while esketamine may be safe to use under the care of a certified healthcare provider, there are reasons to think twice before buying it online.

What is Esketamine?

Esketamine is made from a drug called ketamine. Ketamine has been approved for use as an anesthetic for decades. However, recently, esketamine gained FDA approval for use as a nasal spray for patients with treatment-resistant depression.

Can I Buy Esketamine Online?

As Spravato® becomes more popular for its therapeutic benefits, many patients wonder if there are opportunities to buy esketamine online.

You cannot legally purchase esketamine online. However, many illegal opportunities exist to get ketamine or Spravato on the dark web. But this is never a good idea since it’s still illegal, and the purchase and sale of Spravato are unregulated. Without regulation, no one oversees the purity and veracity of the sellers’ claims, which can be very dangerous since you may not know what you are actually getting when you make a purchase.

Additionally, ketamine is currently listed as a Schedule III compound, which is illegal to possess without full prescribing information. There are also many other reasons to only take Spravato under the supervision of a qualified healthcare provider, such as:

Spravato may be dangerous to take if you have certain underlying health conditions.

Before administering Spravato nasal spray, a clinician will screen you for certain healthcare issues that may cause problems when taking esketamine. These include:

  • Allergies to ketamine
  • Blood vessel disease (aneurysm) in the brain, chest, abdomen, arms, or legs
  • Arteriovenous malformation
  • High blood pressure, as esketamine, often results in increased blood pressure
  • Liver problems
  • History of bleeding in the brain
  • Currently pregnant or breastfeeding
  • Heart problems, including chest pain, heart failure, a heart valve disorder, slow heartbeats, or a previous heart attack or stroke
  • A history of psychosis
  • Alcoholism or drug addiction

Spravato treatments may interact with other drugs.

Therefore, if you take any drugs, you must tell your doctor before beginning Spravato treatment, such as over-the-counter drugs, natural products, and vitamins. Additionally, other prescription medications may be dangerous to take while taking Spravato, such as opioids, sleeping pills, muscle relaxers, anxiety prescriptions, stimulant medicines, pharmaceuticals used to treat narcolepsy, and MAOIs. Full disclosure is vital in avoiding potentially harmful or fatal drug interactions.

Spravato treatment centers know how to administer the nasal spray device.

The reality is that esketamine can be a dangerous drug, especially if it isn’t administered under the care of a medical provider. Spravato should be taken using the following instructions:

  • Through the nose, after the patient has blown their nose.
  • In a healthcare setting where the patient can be monitored.
  • While abstaining from food for at least two hours before administration and liquids for at least a half hour before esketamine use

If an overdose occurs, you will need immediate medical intervention.

When purchasing ketamine online for home use, medical intervention may be delayed leading to long-term effects or death. Patients under a clinician’s care are monitored for two hours after Spravato is administered, ensuring that any immediate dangers have passed before the patient leaves the facility.

You can access the Spravato With Me patient support program.

Janssen Pharmaceuticals has developed Spravato With Me, a patient education and support program, at This program offers financial benefits to lower out-of-pocket costs, personalized treatment support, and patient education materials. It provides treatment centers cost support and allows patient stories to be shared, and can help you find the nearest certified treatment center.

As you can see, taking Spravato can be highly beneficial, but it can be very dangerous when the drug is administered without the proper medical oversight and available safety information. Therefore, it’s never a good idea to take it at home. Additionally, without regulation, it’s also not a good idea to ever purchase this drug online.

Instead, you should use Spravato With Me to access information about local treatment centers and ways to ensure it is affordable for your budget. This is the safest way to use Spravato to treat depression, treatment-resistant depression, or anxiety.

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